Almost but not quite. Canonical description is much closer to bipolar than to unipolar depression, and that is generally how I wrote him in my primary version of the Amberverse. (He was a major part of it because, short version, Fiona was my real Big Bad and was blackmailing Brand into fronting for her.)

Also two more people dealing with missing-body-part issues: Jurt and Coral. Canonically, Coral is fairly traumatized by the loss of her eye and what it was replaced with.

I think that Amber is a particularly interesting setting to write about disability in, because the standard abilities are so far beyond the human norm, and yet they cannot/do not simply serve to negate disabilities, physical or otherwise.