Hello all. I have not yet tested this out but am planning to do so later this week. But there is now a client that can be used with Second Life, which is accessible for users of screen readers. Actually this client has been around for several years, but the original developer passed away and the new one has updated the client. I can't wait to get started with Second Life. Check out this great article: http://onj.me/2xxc- . Last I checked which was just this past weekend, the latest Mac version of Radegast hadn't been posted to the new site but that may have changed by the time you read this.